2RT ( Retinal Rejuvenation Therapy) is a laser therapy for retinal rejuvenation. The 2RT laser treatment is the hope for patients suffering from the initial form of AMD (age-related macular degeneration) to prevent the disease from developing further.
The 2RT laser treatment makes it possible to slow the progression of dry AMD. To date, therapies for age-related macular degeneration have only been implemented to treat late, advanced stages of the disease, when there are already developed signs of damage or vision loss. Retinal rejuvenation therapy through the 2RT procedure makes it possible to intervene earlier and slow down the degeneration process.
What does the 2RT laser treatment consist of?
2RT therapy generates nanosecond, green, Q-switched laser pulses with a wavelength of 532 nm. This makes it possible to precisely and specifically deliver laser energy to the structures of aging RPE (retinal pigment epithelium) cells without causing damage to the retinal photoreceptor cells. The 2RT nanosecond pulse is designed to target only selected, single cells in the indicated epithelial area.
This unique action involves the complete damage and destruction of a small, selected layer of RPE cells which causes neighboring cells to reconstitute a properly functioning pigment epithelial layer. The new cells undergo an adaptation process that releases growth factors and extracellular matrix proteins, which results in better permeability of Bruch’s membrane (located under the epithelium) and restores fluid circulation in the retinal tissues.
How does the 2RT laser work?
Most often, the 2RT laser treatment only needs to be performed once, but it is possible to repeat it. The effect of the treatment appears after 6 months on average. This is the time for the retinal epithelium to rebuild and for neighboring cells to take on an additional role.
Clinical trials of 2RT for AMD
Clinical trials have shown that 2RT can provide therapeutic benefits in the treatment of AMD – similar to those obtained with laser thermal photocoagulation of the retina, but without the collateral damage associated with the conventional method.
Using 500 times less energy than retinal photocoagulation, 2RT reduces the number of drusen and improves the function of both the treated and untreated eye, eliminating the occurrence of thermal damage to the retina and surrounding cells.